AICAR Non-peptide (5‑Aminoimidazole‑4‑carboxamide ribonucleotide) Lyophilized Powder C₉H₁₅N₄O₈P
Molecular Formula: C₉H₁₅N₄O₈P
Molecular Weight: 258.20 g/mol
Cas Number: 2627‑69‑2
Purity: 99.2% HPLC
Length: N/A – 0 Amino, It is a nucleotide analogue, not a peptide
Type: 5‑Aminoimidazole‑4‑carboxamide ribonucleotide
COA (certificate of analysis) provided: aicar_coa_99.20%
Product Video:
AICAR does not contain amino acids, because it is not a peptide. It’s a small‑molecule nucleotide analogue, not a chain of amino acids like Semax, BPC‑157, or ARA‑290.
Why AICAR Has No Amino‑Acid Sequence
Amino‑acid sequences only apply to peptides and proteins. AICAR is a ribonucleotide (a modified AMP precursor), so its structure is built from:
a ribose sugar
a phosphate group
an imidazole‑carboxamide base
No peptide bonds, no amino acids.
What AICAR Actually Is
Full name: 5‑Aminoimidazole‑4‑carboxamide ribonucleotide
Class: AMP analogue / AMPK activator
Function: Mimics cellular energy stress → activates AMPK
The difference between AICAR and peptide‑based AMPK modulators
AICAR is an AMP analogue. Inside cells, it is converted to ZMP, a molecule that looks like AMP to the cell. That “fake AMP” tricks the cell into thinking it’s low on energy.
1. Activates AMPK (the cell’s energy sensor)
AMPK is the master switch for:
increasing energy production
decreasing energy consumption
improving metabolic efficiency
AICAR strongly activates AMPK, which leads to:
increased glucose uptake
increased fatty‑acid oxidation
improved mitochondrial function
reduced inflammation signals
improved insulin sensitivity
This is why AICAR is often described as an exercise‑mimetic at the cellular level.
2. Increases fat oxidation
By activating AMPK, AICAR shifts metabolism toward:
burning stored fat
reducing new fat synthesis
improving lipid profiles
It doesn’t “kill fat cells” like Adipotide; it changes how cells use energy.
3. Enhances endurance in research models
AICAR increases:
mitochondrial biogenesis
muscle glucose uptake
fatigue resistance
In animal studies, it improved endurance without training, because the muscles behave as if they’ve been exercised.
4. Improves cellular stress resistance
AMPK activation leads to:
better autophagy
improved mitochondrial repair
reduced oxidative stress
This is why it’s studied in aging, metabolic disorders, and ischemia.
5. Not a stimulant
AICAR does not:
raise heart rate
increase adrenaline
act on the CNS
Its effects are metabolic, not neurological.
Legal and Safety Information;
Quantum Peptides products are provided exclusively for laboratory research and educational use.
They are not approved for human or veterinary applications.
These materials are not intended to diagnose, treat, cure, or prevent any medical condition.
All use must adhere to applicable laws and regulatory requirements.
“The photo is for illustration purposes only and includes as much product information as possible. Bottle labels wrap around the container and may vary slightly in design & between batches as part of our anti‑counterfeiting measures.”

