Type: Synthetic tripeptide bioregulator (cartilage/connective tissue peptide)

Length: 3 amino acids 

Sequence: Ala–Glu–Asp (AED)

Molecular Formula: C₁₂H₁₉N₃O₈

Molecular Weight: 333.29 g/mol

CAS Number: 85806-95-7

Purity: 99.26% HPLC

COA ( Certificate of Analysis)

Cartalax T-31 (AED) is a synthetic tripeptide bioregulator composed of the amino acid sequence Alanine–Glutamic Acid–Aspartic Acid (Ala-Glu-Asp).

It is being investigated in laboratory settings for its potential role in supporting cartilage cell function, connective tissue metabolism, and extracellular matrix regulation.

Research has explored its influence on chondrocyte activity and collagen-related pathways associated with cartilage maintenance and regeneration.

A synthetic tripeptide with the sequence Alanine–Glutamic Acid–Aspartic acid (Ala‑Glu‑Asp / AED), also called T‑31.

Developed in Russia by the Khavinson group as a peptide bioregulator for cartilage and bone tissue.

What it does (mechanism)

Chondroprotective: protects cartilage cells (chondrocytes) and supports their function.

Regulates the senescence‑associated secretory phenotype (SASP) of aging chondrocytes, reducing pro‑inflammatory and degenerative signaling.

Modulates:

Sirtuin synthesis (cellular aging pathways)

Extracellular matrix remodeling (collagen, aggrecan)

Cytokine production (inflammation).

Acts as a chondroinductive peptide, stimulating markers of cartilage formation (e.g., collagen II, aggrecan, Sox9) in research settings.

Evidence in osteoarthritis

Shows high efficacy in animal OA models, with:

Increased chondrocyte proliferation

Reduced inflammatory cytokines (IL‑1β, TNF‑α)

Preservation of joint structure and improved mobility.

There are oral administration studies in older humans with OA showing benefit, but these are limited and not large randomized trials.

Legal and Safety Information;
Quantum Peptides products are provided exclusively for laboratory research and educational use.
They are not approved for human or veterinary applications.
These materials are not intended to diagnose, treat, cure, or prevent any medical condition.
All use must adhere to applicable laws and regulatory requirements.

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