Type: Human cathelicidin antimicrobial peptide (CAMP)
Length: 37 amino acids
Sequence: (N‑ to C‑terminus): Leu‑Leu‑Gly‑Asp‑Phe‑Phe‑Arg‑Lys‑Ser‑Lys‑Glu‑Lys‑Ile‑Gly‑Lys‑Glu‑Phe‑Lys‑Arg‑Ile‑Val‑Gln‑Arg‑Ile‑Lys‑Asp‑Phe‑Leu‑Arg‑Asn‑Leu‑Val‑Pro‑Arg‑Thr‑Glu‑Ser‑NH₂
Molecular Formula: C₂₀₅H₃₄₀N₆₀O₅₃
Molecular Weight: 4493.3 g/mol

CAS Number: 154947‑66‑7
Purity: 99.19% HPLC

COA ( Certificate of Analysis) LL-37 COA 99.19

Product Video:

LL‑37 Cathelicidin plays several roles in human immunity and tissue defense, and its actions extend well beyond simply killing microbes. It is one of the most studied human host‑defense peptides, and its functions span antimicrobial activity, immune modulation, and tissue repair.

Antimicrobial and antiviral actions

LL‑37 Cathelicidin   disrupts the membranes of bacteria, fungi, and viruses, giving it broad‑spectrum antimicrobial activity. It is highlighted as having potent antibacterial, antiviral, antifungal, antiparasitic, and even antitumor properties.

Immune‑modulating effects

LL‑37 helps regulate innate immunity. It binds and neutralizes bacterial endotoxins and promotes chemotaxis, guiding immune cells to sites of infection or injury.

Host‑defense signaling

LL‑37 is produced by many cell types, including epithelial cells, neutrophils, macrophages, lymphocytes, and keratinocytes. Its expression is influenced by inflammatory cytokines, growth factors, and vitamin D, placing it at the intersection of immune activation and tissue protection.

Tissue repair and wound healing

Beyond killing pathogens, LL‑37 supports wound healing by promoting cell migration, angiogenesis, and tissue remodeling. These effects make it a focus of research in regenerative medicine and chronic wound care.

Anti‑endotoxin activity

By binding bacterial lipopolysaccharides, LL‑37 reduces excessive inflammatory responses, helping prevent tissue damage during infection.

Therapeutic interest

Because of its broad activity, LL‑37 is being explored for next‑generation antimicrobial and immunomodulatory therapies, although challenges such as stability and cytotoxicity still limit clinical use.

Legal and Safety Information;
Quantum Peptides products are provided exclusively for laboratory research and educational use.
They are not approved for human or veterinary applications.
These materials are not intended to diagnose, treat, cure, or prevent any medical condition.
All use must adhere to applicable laws and regulatory requirements.

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