PEG MGF (24 Amino) Peptide Lyophilized powder C₁₂₁H₂₀₀N₄₂O₃₉ + C₂H₄Oₙ
Type: Pegylated peptide hormone,
Length: 24 amino acids
Sequence: Tyr–Gln–Pro–Pro–Ser–Thr–Asn–Lys–Asn–Thr–Lys–Ser–Gln–Arg–Arg–Lys–Gly–Ser–Thr–Phe–Glu–Glu–Arg–Lys
Molecular Formula: C₁₂₁H₂₀₀N₄₂O₃₉ + C₂H₄Oₙ
Molecular Weight: 2948.1 g/mol
CAS Number: N/A
Purity: 99.01% HPLC
COA ( Certificate of Analysis) PEG MGF COA 99.01
PEG‑MGF acts as a long‑acting, muscle‑repair and regeneration signal, created by attaching polyethylene glycol (PEG) to the native Mechano Growth Factor (MGF) peptide.
This modification dramatically allows it to exert broader effects on muscle tissue, recovery, and cellular repair.y extends its half‑life.
Core biological actions
PEG‑MGF is a pegylated splice‑variant of IGF‑1, produced naturally in muscle after mechanical stress. Pegylation stabilizes the molecule, allowing it to remain active for hours instead of minutes. This extended activity lets it influence several key processes:
- Satellite‑cell activation — It stimulates muscle stem cells responsible for repair and new fiber formation.
- Myoblast division and fusion — It promotes the creation and maturation of new muscle cells, supporting hypertrophy.
- Muscle‑fiber repair — It enhances the repair of damaged fibers following intense training or injury.
- Protein synthesis — It increases anabolic signaling, contributing to muscle growth.
Regeneration and healing
PEG‑MGF has documented regenerative effects across multiple tissues:
- Accelerated recovery through increased recruitment of neutrophils and macrophages to injury sites.
- Nerve regeneration and neuroprotective effects.
- Support for tendon, ligament, and bone repair, making it relevant in broader tissue‑healing research.
Anti‑inflammatory and protective effects
Research summaries describe additional actions:
- Reduced inflammation in muscle tissue.
- Protection of cardiac muscle via reduced apoptosis and enhanced cardiac stem‑cell proliferation.
Performance and adaptation
Because of its extended half‑life and regenerative profile, PEG‑MGF is associated with:
- Improved training recovery
- Enhanced muscle endurance
- Increased strength gains
- Reduced risk of overuse injuries
- Better adaptation to training stimuli
Why PEG‑MGF exists
Native MGF has a 5–7 minute half‑life, making it impractical for research. Pegylation extends this to hours, enabling sustained biological activity and making PEG‑MGF far more effective for studying muscle repair and regeneration.
Legal and Safety Information;
Quantum Peptides products are provided exclusively for laboratory research and educational use.
They are not approved for human or veterinary applications.
These materials are not intended to diagnose, treat, cure, or prevent any medical condition.
All use must adhere to applicable laws and regulatory requirements.
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