Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Weight: 639.8 g/mol
Cas Number: 736992‑21‑5
Purity: 99.18% HPLC
Length: 4 amino acids
Type: Synthetic mitochondria‑targeted peptide
COA (certificate of analysis) provided: ss-31_coa_99.18%

Product Video:

🧬 SS‑31 (Elamipretide)

What it is
SS‑31 is a synthetic tetrapeptide designed to target and protect mitochondria. Its sequence is:
D‑Arg – Dmt – Lys – Phe‑NH₂ (Dmt = 2’,6’-dimethyl‑tyrosine)
This compact structure gives it unusually strong mitochondrial affinity.

🔬 How it works
SS‑31 binds selectively to cardiolipin, a phospholipid found only in the inner mitochondrial membrane. This interaction helps:

Stabilize mitochondrial structure

Improve electron transport chain efficiency

Reduce reactive oxygen species

Enhance ATP production

It’s one of the few peptides engineered specifically for mitochondrial repair and bioenergetic support.

🧪 Key chemical properties

Molecular formula: C₃₂H₄₉N₉O₅

Molecular weight: ~639.8 g/mol

Charge: Highly cationic (due to D‑Arg and Lys)

Size: 4 amino acids (very small for a bioactive peptide)

Its small size and positive charge help it cross membranes and accumulate inside mitochondria.

Why researchers study it
SS‑31 has been investigated for its potential roles in:

Mitochondrial myopathies

Heart failure

Kidney injury

Neurodegeneration

Age‑related mitochondrial decline

Muscle performance and recovery

Its mechanism is unique because it doesn’t just reduce oxidative stress—it improves mitochondrial efficiency at the source.

What makes SS‑31 special

Targets mitochondria without needing a targeting sequence

Works at nanomolar concentrations

Protects cardiolipin from peroxidation

Enhances ATP output

Reduces mitochondrial swelling and cytochrome c release

It’s essentially a mitochondrial stabilizer.

Legal and Safety Information;
Quantum Peptides products are provided exclusively for laboratory research and educational use.
They are not approved for human or veterinary applications.
These materials are not intended to diagnose, treat, cure, or prevent any medical condition.
All use must adhere to applicable laws and regulatory requirements.

“The photo is for illustration purposes only and includes as much product information as possible. Bottle labels wrap around the container and may vary slightly in design & between batches as part of our anti‑counterfeiting measures.”